Article
GLUT12 deficiency during early development results in heart failure and a diabetic phenotype in zebrafish.
The Journal of endocrinology - 1 Jan 2015
Jiménez-Amilburu Vanesa, Jong-Raadsen Susanne, Bakkers Jeroen, Spaink Herman P, Marín-Juez Rubén
Abstract excerpt
Cardiomyopathies-associated metabolic pathologies (e.g., type 2 diabetes and insulin resistance) are a leading cause of mortality. It is known that the association between these pathologies works in both directions, for which heart failure can lead to metabolic derangements such as insulin resistance. This intricate crosstalk exemplifies the importance of a fine coordination between one of the most...
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