Profile of common prostate cancer risk variants in an unscreened Romanian population.

doi:10.1111/jcmm.13433

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Article

Profile of common prostate cancer risk variants in an unscreened Romanian population.

Journal of cellular and molecular medicine - 1 Mar 2018

Iordache Paul D, Mates Dana, Gunnarsson Bjarni, Eggertsson Hannes P, Sulem Patrick, Guðmundsson Júlíus, Benónísdóttir Stefania, Csiki Irma Eva, Rascu Stefan, Radavoi Daniel, Ursu Radu, Staicu Catalin, Calota Violeta, Voinoiu Angelica, Jinga Mariana, Rosoga Gabriel, Danau Razvan, Sima Sorin Cristian, Badescu Daniel, Suciu Nicoleta, Radoi Viorica, Manolescu Andrei, Rafnar Thorunn, Halldórsson Bjarni V, Jinga Viorel, Stefánsson Kári

Abstract excerpt

To find sequence variants affecting prostate cancer (PCA) susceptibility in an unscreened Romanian population we use a genome-wide association study (GWAS). The study population included 990 unrelated pathologically confirmed PCA cases and 1034 male controls. DNA was genotyped using Illumina SNP arrays, and 24.295.558 variants were imputed using the 1000 Genomes data set. An association test was performed between...

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Identifiers

PMID: 29266682
DOI: 10.1111/jcmm.13433
PMCID: PMC5824401

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