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Article

Germline Variants in DNA Repair Genes, Diagnostic Radiation, and Risk of Thyroid Cancer.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Mar 2018

Sandler Jason E, Huang Huang, Zhao Nan, Wu Weiwei, Liu Fangfang, Ma Shuangge, Udelsman Robert, Zhang Yawei

Abstract excerpt

Background: Radiation exposure is a well-documented risk factor for thyroid cancer; diagnostic imaging represents an increasing source of exposure. Germline variations in DNA repair genes could increase risk of developing thyroid cancer following diagnostic radiation exposure. No studies have directly tested for interaction between germline mutations and radiation exposure.Methods: Using data and DNA samples from...

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Share to Carcinoma, Papillary
Share to DNA Modification Methylases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 29263185
DOI: 10.1158/1055-9965.EPI-17-0319
PMCID: PMC6426634

Genes

MGMT

Provenance

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