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Article

A novel human pain insensitivity disorder caused by a point mutation in ZFHX2

16 Nov 2017

Abstract excerpt

Chronic pain is a major global public health issue causing a severe impact on both the quality of life for sufferers and the wider economy. Despite the significant clinical burden, little progress has been made in terms of therapeutic development. A unique approach to identifying new human-validated analgesic drug targets is to study rare families with inherited pain insensitivity. Here we have analysed an...

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Share to Hereditary Neurological Disorders
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29253101
DOI: 10.1093/brain/awx326

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