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The Role of Mitochondrial Dynamics and Mitophagy in Carcinogenesis, Metastasis and Therapy

10 Jun 2020

Abstract excerpt

Mitochondria are key cellular organelles and play vital roles in energy metabolism, apoptosis regulation and cellular homeostasis. Mitochondrial dynamics refers to the varying balance between mitochondrial fission and mitochondrial fusion that plays an important part in maintaining mitochondrial homeostasis and quality. Mitochondrial malfunction is involved in aging, metabolic disease, neurodegenerative...

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Identifiers

PMID: 32587855
DOI: 10.3389/fcell.2020.00413

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