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An epigenome-wide DNA methylation study of PTSD and depression in World Trade Center responders

27 Jun 2017

Abstract excerpt

Previous epigenome-wide association studies (EWAS) of posttraumatic stress disorder (PTSD) and major depressive disorder (MDD) have been inconsistent. This may be due to small sample sizes, and measurement and tissue differences. The current two EWA analyses of 473 World Trade Center responders are the largest to date for both PTSD and MDD. These analyses investigated DNA methylation patterns and biological...

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PMID: 28654093
DOI: 10.1038/tp.2017.130

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