Article
DNA and RNA-sequence based GWAS highlights membrane-transport genes as key modulators of milk lactose content.
BMC genomics - 15 Dec 2017
Lopdell Thomas J, Tiplady Kathryn, Struchalin Maksim, Johnson Thomas J J, Keehan Michael, Sherlock Ric, Couldrey Christine, Davis Stephen R, Snell Russell G, Spelman Richard J, Littlejohn Mathew D
Abstract excerpt
BACKGROUND: Lactose provides an easily-digested energy source for neonates, and is the primary carbohydrate in milk in most species. Bovine lactose is also a key component of many human food products. However, compared to analyses of other milk components, the genetic control of lactose has been little studied. Here we present the first GWAS focussed on analysis of milk lactose traits. RESULTS: Using a discovery...
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