Article
Bridging GWAS to genes: an integrative multi-omics approach using cattle data.
BMC genomics - 14 Jan 2026
Ghoreishifar Mohammad, Macleod Iona M, Nguyen Tuan, Lopdell Thomas J, Littlejohn Mathew D, Xiang Ruidong, Chamberlain Amanda J, Pryce Jennie E, Goddard Michael E
Abstract excerpt
BACKGROUND: Genome-wide association studies (GWASs) have identified thousands of loci for complex traits, but pinpointing causal variants and linking them to target genes remains challenging. Several strategies have been proposed to address these challenges, e.g., comparisons across the genome, using larger and multi-breed datasets, multi-trait analyses, leveraging multi-omics data, etc. RESULTS: We used a...
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