Article
Within-breed and multi-breed GWAS on imputed whole-genome sequence variants reveal candidate mutations affecting milk protein composition in dairy cattle.
Genetics, selection, evolution : GSE - 18 Sept 2017
Sanchez Marie-Pierre, Govignon-Gion Armelle, Croiseau Pascal, Fritz Sébastien, Hozé Chris, Miranda Guy, Martin Patrice, Barbat-Leterrier Anne, Letaïef Rabia, Rocha Dominique, Brochard Mickaël, Boussaha Mekki, Boichard Didier
Abstract excerpt
BACKGROUND: Genome-wide association studies (GWAS) were performed at the sequence level to identify candidate mutations that affect the expression of six major milk proteins in Montbéliarde (MON), Normande (NOR), and Holstein (HOL) dairy cattle. Whey protein (α-lactalbumin and β-lactoglobulin) and casein (αs1, αs2, β, and κ) contents were estimated by mid-infrared (MIR) spectrometry, with medium to high accuracy...
Topics
- Animals
- Breeding
- Cattle
- Female
- Genetic Variation
- Genome
- Genome-Wide Association Study
- Lactation
- Male
- Milk