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Article

Association between HLA-DRB10405, -DQB10401 and -DQA1*0303 alleles and lamotrigine-induced cutaneous adverse drug reactions. A pilot case-control study from Japan.

Journal of affective disorders - 1 Jul 2015

Ito Akiko, Shimada Hiromitsu, Ishikawa Kazushi, Takeo Naoko, Hatano Yutaka, Katagiri Kazumoto, Kohno Kentaro, Araki Yasuo, Terao Takeshi, Kojima Hiroto, Terao Chikashi, Eshima Nobuoki, Fujiwara Sakuhei

Abstract excerpt

BACKGROUND: Human leukocyte antigen (HLA) genotypes in lamotrigine -induced (LTG-induced) cutaneous adverse drug reactions (cADRs) have been described in several reports but controversy remains even for a given ethnic group. We attempted to clarify a possible association between LTG-induced cADRs and HLA alleles in Japanese patients. METHOD: Sixteen subjects, including eight patients with LTG-induced cADRs and...

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PMID: 25845749
DOI: 10.1016/j.jad.2015.03.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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