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Article

The Significance of TROP2 Expression in Predicting BRAF Mutations in Papillary Thyroid Carcinoma

11 Dec 2017

Abstract excerpt

Background: Trophoblast antigen 2 (TROP2) is a human trophoblast cell-surface glycoprotein that is overexpressed in several types of epithelial cancers, and is suggested to be associated with an unfavorable prognosis. BRAF mutations are the most common genetic alteration in papillary thyroid carcinoma (PTC). We evaluated the correlation between TROP2 expression and BRAF mutation in PTC. Methods: First, we carried...

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PMID: 29228520
DOI: 10.4132/jptm.2017.10.17

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