Article
Neuropilin-2 promotes growth and progression of papillary thyroid cancer cells.
Auris, nasus, larynx - 1 Oct 2020
Lee Geonho, Kang Yea Eun, Oh Chan, Liu Lihua, Jin Yanli, Lim Mi Ae, Won Ho-Ryun, Chang Jae Won, Koo Bon Seok
Abstract excerpt
OBJECTIVE: Neuropilin-2 (NRP2) is a coreceptor of vascular endothelial growth factor-C/D (VEGF-C/D) and plays the important role in the development of lymphatic endothelial cells, as well as neuronal development. NRP2 is known to affect aggressiveness by increasing expression in various human cancers, but the role of NRP2 in thyroid cancer is not fully understood. The purpose of this study was to investigate the...
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