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Article

TROP2 promotes cell proliferation and migration in osteosarcoma through PI3K/AKT signaling

29 May 2018

Abstract excerpt

Human trophoblast cell surface antigen 2 (TROP2) has been noted to serve an important role in the proliferation and migration of various types of human cancers. However, the potential role and the molecular mechanisms of TROP2 in osteosarcoma (OS) remain largely unclear. In the present study, high expression of TROP2 in human OS tissues and cell lines was observed. Overexpression of TROP2 promoted the...

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Identifiers

PMID: 29845216
DOI: 10.3892/mmr.2018.9083

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