Article
Switching the polarity of a bacteriophage integration system.
Molecular microbiology - 1 Mar 2004
Smith Matthew C A, Till Rob, Smith Margaret C M
Abstract excerpt
During lysogenic growth many temperate bacteriophage genomes are integrated into the host's chromosome and efficient integration and excision are therefore an essential part of the phage life cycle. The Streptomyces phage phiC31 encodes an integrase related to the resolvase/invertases and is evolutionarily and mechanistically distinct from the integrase of phage lambda. We show that during phiC31 integration the...
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