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Article

Psychiatric polygenic risk associates with cortical morphology and functional organization in aging.

Translational psychiatry - 11 Dec 2017

Lee Annie, Shen Mojun, Qiu Anqi

Abstract excerpt

Common brain abnormalities in cortical morphology and functional organization are observed in psychiatric disorders and aging, reflecting shared genetic influences. This preliminary study aimed to examine the contribution of a polygenetic risk for psychiatric disorders (PRScross) to aging brain and to identify molecular mechanisms through the use of multimodal brain images, genotypes, and transcriptome data. We...

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Identifiers

PMID: 29225336
DOI: 10.1038/s41398-017-0036-z
PMCID: PMC5802582

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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