Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Adiponectin Deficiency Impairs Maternal Metabolic Adaptation to Pregnancy in Mice

10 Jan 2017

Abstract excerpt

Hypoadiponectinemia has been widely observed in patients with gestational diabetes mellitus (GDM). To investigate the causal role of hypoadiponectinemia in GDM, adiponectin gene knockout (Adipoq−/−) and wild-type (WT) mice were crossed to produce pregnant mouse models with or without adiponectin deficiency. Adenoviral vector–mediated in vivo transduction was used to reconstitute adiponectin during late pregnancy....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Birth, Development, and Health
Share to Gestational Diabetes Research and Management

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28073830
DOI: 10.2337/db16-1096

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Adiponectin Deficiency Impairs Maternal Metabolic Adaptation to Pregnancy in MicePMID 28073830Read ↗

Acute loss of adipose tissue-derived adiponectin triggers immediate metabolic deterioration in mice.Semantic proximity Read ↗

Effects of Exogenous Adiponectin Supplementation in Early Pregnant PCOS Mice on the Metabolic Syndrome of Adult Female OffspringSemantic proximity Read ↗

Adverse adipose phenotype and hyperinsulinemia in gravid mice deficient in placental growth factor.Semantic proximity Read ↗

Altered metabolic health during pregnancy in mice with lean polycystic ovary syndrome-like traits from high prenatal AMHSemantic proximity Read ↗

Monoacylglycerol O-acyltransferase 1 is required for adipocyte differentiation <i>in vitro</i> but does not affect adiposity in miceSemantic proximity Read ↗

Maternal age, obesity and hyperglycaemia are associated with a delay in preimplantation embryo development in mouseSemantic proximity Read ↗

A Novel<i>ADIPOQ</i>Mutation (p.M40K) Impairs Assembly of High-Molecular-Weight Adiponectin and Is Associated With Early-Onset Obesity and Metabolic SyndromeSemantic proximity Read ↗

Adiponectin in human pregnancy: implications for regulation of glucose and lipid metabolismSemantic proximity Read ↗

Parental diet-induced obesity leads to retarded early mouse embryo development and altered carbohydrate utilisation by the blastocyst.Semantic proximity Read ↗

Insulin Increases Adipose Adiponectin in Pregnancy by Inhibiting Ubiquitination and Degradation: Impact of ObesitySemantic proximity Read ↗

A mouse model of gestational diabetes shows dysregulated lipid metabolism post-weaning, after return to euglycaemiaSemantic proximity Read ↗

Adiponectin and adiponectin receptors in obesity-linked insulin resistance.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.