The UGT1A1*28 gene variant predicts long-term mortality in patients undergoing coronary angiography.

doi:10.1515/cclm-2017-0692

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The UGT1A1*28 gene variant predicts long-term mortality in patients undergoing coronary angiography.

Clinical chemistry and laboratory medicine - 28 Mar 2018

Zulus Barbara, Grünbacher Gerda, Kleber Marcus E, März Winfried, Renner Wilfried

Abstract excerpt

BACKGROUND: Uridine diphosphate glycosyltransferases 1A1 (UGT1A1) plays an essential role in detoxification and excretion of several endogenous and exogenous compounds. A functional polymorphism in the promoter of the UGT1A1 gene (TA repeat insertion, UGT1A1*28, rs3064744) has been associated with reduced UGT1A1 enzyme activity. The purpose of the present study was to investigate the role of UGT1A1 genotypes in...

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PMID: 29220881
DOI: 10.1515/cclm-2017-0692

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