Article
ABCA1 impacts athero-thrombotic risk and 10-year survival in a contemporary secondary prevention setting.
Atherosclerosis - 1 Oct 2011
Regieli Jakub J, Doevendans Pieter A, Grobbee Diederick E, Zwinderman Aeilko H, van der Graaf Yolanda, Kastelein John J P, Jukema J Wouter
Abstract excerpt
OBJECTIVES: We prospectively investigated the effects of ATP-binding cassette protein-1 (ABCA1) variants on long-term clinical outcome in patients with coronary artery disease (CAD). BACKGROUND: ABCA1 is implicated in the etiology of atherothrombosis and may offer a target to reduce cardiovascular risk. However, the impact of ABCA1 on recurrent cardiovascular disease in a secondary prevention setting is as of yet...
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