Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Computational identification of harmful mutation regions to the activity of transposable elements.

BMC genomics - 17 Nov 2017

Jin Lingling, McQuillan Ian, Li Longhai

Abstract excerpt

BACKGROUND: Transposable elements (TEs) are interspersed DNA sequences that can move or copy to new positions within a genome. TEs are believed to promote speciation and their activities play a significant role in human disease. In the human genome, the 22 AluY and 6 AluS TE subfamilies have been the most recently active, and their transposition has been implicated in many inherited human diseases and in various...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alu Elements
Share to Computational Biology
Share to DNA Transposable Elements

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Evolution, Molecular

Share to Genome, Human

Share to Models, Genetic

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 29219079
DOI: 10.1186/s12864-017-4227-z
PMCID: PMC5773891

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Computational identification of harmful mutation regions to the activity of transposable elements.PMID 29219079Read ↗

Transposon clusters as substrates for aberrant splice-site activation.Semantic proximity Read ↗

A high throughput screen for active human transposable elements.Semantic proximity Read ↗

Strong and Fluctuating Sequence Constraints Drive <i>Alu_</i> EvolutionSemantic proximity Read ↗

The transposable element environment of human genes is associated with histone and expression changes in cancer.Semantic proximity Read ↗

Transposable elements: an abundant and natural source of regulatory sequences for host genes.Semantic proximity Read ↗

Active Alu retrotransposons in the human genome.Semantic proximity Read ↗

Transposable elements in disease-associated cryptic exons.Semantic proximity Read ↗

Exploring Alu-Driven DNA Transductions in the Primate GenomesSemantic proximity Read ↗

DNA methylation enables transposable element-driven genome expansion.Semantic proximity Read ↗

Impact of transposable elements on the human genome.Semantic proximity Read ↗

Exploring <i>Alu</i> -Driven DNA Transductions in the Primate GenomesSemantic proximity Read ↗

Distributions of transposable elements reveal hazardous zones in mammalian introns.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.