Article
Distributions of transposable elements reveal hazardous zones in mammalian introns.
PLoS computational biology - 1 May 2011
Zhang Ying, Romanish Mark T, Mager Dixie L
Abstract excerpt
Comprising nearly half of the human and mouse genomes, transposable elements (TEs) are found within most genes. Although the vast majority of TEs in introns are fixed in the species and presumably exert no significant effects on the enclosing gene, some markedly perturb transcription and result in disease or a mutated phenotype. Factors determining the likelihood that an intronic TE will affect transcription are...
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