Article
Genome-Wide Association Study Meta-Analysis of Long-Term Average Blood Pressure in East Asians.
Circulation. Cardiovascular genetics - 1 Apr 2017
Li Changwei, Kim Yun Kyoung, Dorajoo Rajkumar, Li Huaixing, Lee I-Te, Cheng Ching-Yu, He Meian, Sheu Wayne H-H, Guo Xiuqing, Ganesh Santhi K, He Jiang, Lee Juyoung, Liu Jianjun, Hu Yao, Rao Dabeeru C, Tsai Fuu-Jen, Koh Jia Yu, Hu Hua, Liang Kae-Woei, Palmas Walter, Hixson James E, Han Sohee, Teo Yik-Ying, Wang Yiqin, Chen Jing, Lu Chieh Hsiang, Zheng Yingfeng, Gui Lixuan, Lee Wen-Jane, Yao Jie, Gu Dongfeng, Han Bok-Ghee, Sim Xueling, Sun Liang, Zhao Jinying, Chen Chien-Hsiun, Kumari Neelam, He Yunfeng, Taylor Kent D, Raffel Leslie J, Moon Sanghoon, Rotter Jerome I, Ida Chen Yii-der, Wu Tangchun, Wong Tien Yin, Wu Jer-Yuarn, Lin Xu, Tai E-Shyong, Kim Bong-Jo, Kelly Tanika N
Abstract excerpt
BACKGROUND: Genome-wide single marker and gene-based meta-analyses of long-term average (LTA) blood pressure (BP) phenotypes may reveal novel findings for BP. METHODS AND RESULTS: We conducted genome-wide analysis among 18 422 East Asian participants (stage 1) followed by replication study of ≤46 629 participants of European ancestry (stage 2). Significant single-nucleotide polymorphisms and genes were determined...
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