Article
Identification of six novel susceptibility loci for dyslipidemia using longitudinal exome-wide association studies in a Japanese population.
Genomics - 1 Jul 2019
Yasukochi Yoshiki, Sakuma Jun, Takeuchi Ichiro, Kato Kimihiko, Oguri Mitsutoshi, Fujimaki Tetsuo, Horibe Hideki, Yamada Yoshiji
Abstract excerpt
Recent genome-wide association studies have identified various dyslipidemia-related genetic variants. However, most studies were conducted in a cross-sectional manner. We thus performed longitudinal exome-wide association studies of dyslipidemia in a Japanese population. We used ~244,000 genetic variants and clinical data of 6022 Japanese individuals who had undergone annual health checkups for several years....
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