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Article

Genetic Risk of Primary Aldosteronism and Its Contribution to Hypertension: A Cross-Ancestry Meta-Analysis of Genome-Wide Association Studies.

Circulation - 4 Apr 2023

Naito Tatsuhiko, Inoue Kosuke, Sonehara Kyuto, Baba Ryuta, Kodama Takaya, Otagaki Yu, Okada Akira, Itcho Kiyotaka, Kobuke Kazuhiro, Kishimoto Shinji, Yamamoto Kenichi, Morisaki Takayuki, Higashi Yukihito, Hinata Nobuyuki, Arihiro Koji, Hattori Noboru, Okada Yukinori, Oki Kenji

Abstract excerpt

BACKGROUND: Hypertension imposes substantial health and economic burden worldwide. Primary aldosteronism (PA) is one of the most common causes of secondary hypertension, causing cardiovascular events at higher risk compared with essential hypertension. However, the germline genetic contribution to the susceptibility of PA has not been well elucidated. METHOD: We conducted a genome-wide association analysis of PA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36802911
DOI: 10.1161/CIRCULATIONAHA.122.062349
PMCID: PMC10063185

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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