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Article

Nobiletin induces brown adipocyte-like phenotype and ameliorates stress in 3T3-L1 adipocytes.

Biochimie - 1 Mar 2018

Lone Jameel, Parray Hilal Ahmad, Yun Jong Won

Abstract excerpt

Browning of white adipocytes (beiging) is an attractive therapeutic strategy against obesity and its associated metabolic complications. Nobiletin (NOB) is a polymethoxylated flavone present in citrus fruits and has been reported to have anti-obesity effects. Here, we report that nobiletin exerts dual modulatory effects on adipocytes via induction of browning in 3T3-L1 white adipocytes and amelioration of stress...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29217172
DOI: 10.1016/j.biochi.2017.11.021

Genes

ACOX1
FAS
JUN
PGC
SIRT1
UCP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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