Article
Lycopene attenuates body weight gain through induction of browning via regulation of peroxisome proliferator-activated receptor γ in high-fat diet-induced obese mice.
The Journal of nutritional biochemistry - 1 Apr 2020
Zhu Ruyuan, Wei Junping, Liu Haixia, Liu Chenyue, Wang Lili, Chen Beibei, Li Lin, Jia Qiangqiang, Tian Yimiao, Li Rui, Zhao Dandan, Mo Fangfang, Li Yu, Gao Sihua, Wang Xiang-Dong, Zhang Dongwei
Abstract excerpt
Lycopene (LYC), one of the major carotenoids in tomatoes, has been preclinically and clinically used to obesity and type 2 diabetes management. However, whether its ability of countering body weight gain is related to induction of brown-like adipocyte phenotype in white adipose tissues (WAT) remains largely unknown. Activation of peroxisome proliferator-activated receptor γ (PPARγ) serves the brown-like phenotype...
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