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Quercetin 3-O-glucuronide-rich lotus leaf extract promotes a Brown-fat-phenotype in C3H10T1/2 mesenchymal stem cells.

Food research international (Ottawa, Ont.) - 1 Jan 2023

Wang Zhenyu, Xue Chaoyi, Wang Xuan, Zeng Maomao, Wang Zhaojun, Chen Qiuming, Chen Jie, Christian Mark, He Zhiyong

Abstract excerpt

Lotus (Nelumbo nucifera Gaertn.) is an aquatic perennial crop planted worldwide and its leaf (also called "He-Ye") has therapeutic effects on obesity. However, whether the underlying mechanism leads to increased energy expenditure by activation of brown adipocytes has not been clarified. Here, murine C3H10T1/2 mesenchymal stem cells (MSCs) were employed to investigate the effects of ethanol extracts from lotus...

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PMID: 36596137
DOI: 10.1016/j.foodres.2022.112198

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