Article
Metformin and vitamin D modulate adipose-derived stem cell differentiation towards the beige phenotype.
Adipocyte - 1 Dec 2022
Cruciani Sara, Garroni Giuseppe, Pala Renzo, Coradduzza Donatella, Cossu Maria Laura, Ginesu Giorgio Carlo, Capobianco Giampiero, Dessole Salvatore, Ventura Carlo, Maioli Margherita
Abstract excerpt
Adipose-derived stem cells (ADSCs) represent an ideal stem cell population for regenerative medicine. ADSC adipogenic differentiation is controlled by the activation of a specific transcriptional program, including epigenetic factors and key adipogenic genes. Under certain conditioned media, ADSCs can differentiate into several phenotypes. We previously demonstrated that bioactive molecules could counteract lipid...
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