Article
Chrousos syndrome: from molecular pathogenesis to therapeutic management.
European journal of clinical investigation - 1 May 2015
Nicolaides Nicolas C, Charmandari Evangelia
Abstract excerpt
BACKGROUND: Primary Generalized Glucocorticoid Resistance or Chrousos syndrome is a rare genetic condition characterized by end-organ insensitivity to glucocorticoids owing to inactivating mutations of the NR3C1 gene. MATERIALS AND METHODS: We conducted a systematic review of the published, peer-reviewed medical literature using MEDLINE (1975 through November 2014) to identify original articles and reviews on...
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