Article
Blood collection in cell-stabilizing tubes does not impact germline DNA quality for pediatric patients.
PloS one - 1 Jan 2017
Wollison Bruce M, Thai Edwin, Mckinney Aimee, Ward Abigail, Clapp Andrea, Clinton Catherine, Nag Anwesha, Thorner Aaron R, Gastier-Foster Julie M, Crompton Brian D
Abstract excerpt
OBJECTIVES: Liquid biopsy technologies allow non-invasive tumor profiling for patients with solid tumor malignancies by sequencing circulating tumor DNA. These studies may be useful in risk-stratification, monitoring for relapse, and understanding tumor evolution. The quality of DNA obtained for these studies is improved when blood samples are collected in tubes that stabilizing white blood cells (WBC). However,...
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