Article
Comparison of Blood Collection Tubes from Three Different Manufacturers for the Collection of Cell-Free DNA for Liquid Biopsy Mutation Testing.
The Journal of molecular diagnostics : JMD - 1 Sept 2017
Alidousty Christina, Brandes Danielle, Heydt Carina, Wagener Svenja, Wittersheim Maike, Schäfer Stephan C, Holz Barbara, Merkelbach-Bruse Sabine, Büttner Reinhard, Fassunke Jana, Schultheis Anne M
Abstract excerpt
The improvement in sensitive techniques has allowed the detection of tumor-specific aberrations in circulating tumor (ct) DNA. Amplification-refractory mutation system PCR has been used for the analysis of ctDNA to detect resistance-causing mutations in the epidermal growth factor receptor gene (eg, EGFR T790M) in lung cancer patients. So far, Streck tubes have been widely used as standard blood collection tubes....
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