Article
Systemic Markers of Adaptive and Innate Immunity Are Associated with Chronic Obstructive Pulmonary Disease Severity and Spirometric Disease Progression.
American journal of respiratory cell and molecular biology - 1 Apr 2018
Halper-Stromberg Eitan, Yun Jeong H, Parker Margaret M, Singer Ruth Tal, Gaggar Amit, Silverman Edwin K, Leach Sonia, Bowler Russell P, Castaldi Peter J
Abstract excerpt
The progression of chronic obstructive pulmonary disease (COPD) is associated with marked alterations in circulating immune cell populations, but no studies have characterized alterations in these cell types across the full spectrum of lung function impairment in current and former smokers. In 6,299 subjects from the COPDGene and ECLIPSE (Evaluation of COPD Longitudinally to Identify Predictive Surrogate...
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