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SeekDeep: single-base resolution de novo clustering for amplicon deep sequencing.

Nucleic acids research - 28 Feb 2018

Hathaway Nicholas J, Parobek Christian M, Juliano Jonathan J, Bailey Jeffrey A

Abstract excerpt

PCR amplicon deep sequencing continues to transform the investigation of genetic diversity in viral, bacterial, and eukaryotic populations. In eukaryotic populations such as Plasmodium falciparum infections, it is important to discriminate sequences differing by a single nucleotide polymorphism. In bacterial populations, single-base resolution can provide improved resolution towards species and strains. Here, we...

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PMID: 29202193
DOI: 10.1093/nar/gkx1201
PMCID: PMC5829576

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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