Article

MetaScope: A High-Resolution Framework for Species-Level 16S Metataxonomic Classification

2025-09-04

Abstract excerpt

Accurate species-level classification of microbial communities remains a major challenge in microbiome analysis, particularly when using traditional 16S rRNA amplicon sequencing pipelines such as QIIME2 and DADA2. These methods often fail to resolve taxonomy beyond the genus level due to limitations in clustering algorithms and ambiguous marker genes. To address this, we present MetaScope, a modular, R-based softw...

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Literature Corpus work: 2739ea43-9ba3-5261-8379-cea4d8df0bef
DOI: 10.1101/2025.08.29.673160

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