Article
cgDist: Nucleotide-level distance calculation from cgMLST allelic profiles.
NAR genomics and bioinformatics - 1 Sept 2026
de Ruvo Andrea, Castelli Pierluigi, Bucciacchio Andrea, Mangone Iolanda, Mixão Verónica, Borges Vítor, Flammini Michele, Radomski Nicolas, Di Pasquale Adriano
Abstract excerpt
Bacterial genomic surveillance requires balancing computational efficiency with genetic resolution for effective cluster investigation. cgMLST distance calculations treat all allelic differences as equivalent units, obscuring nucleotide-level variation. Furthermore, single nucleotide polymorphism-based pipelines provide finer resolution at substantially higher computational cost, which limits their routine...
Read the complete abstract on PubMedTopics
- Algorithms
- Polymorphism, Single Nucleotide
- Alleles
- Software
- Genome, Bacterial