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Article

Testicular orphan receptor 4 promotes tumor progression and implies poor survival through AKT 3 regulation in seminoma

2 Dec 2017

Abstract excerpt

Seminoma is the most common testicular germ cell tumor worldwide and mainly occurs in 15-35-year-old young men. Early studies have indicated that testicular nuclear receptor 4 (TR4) first cloned from testis is involved in the invasion and metastasis of several human tumors; however, little attention is paid to the function of TR4 in seminoma. Our immunohistochemical (IHC) staining results showed that patients...

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PMID: 29197138
DOI: 10.1111/cas.13461

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