Article
PAX8 expression and TERT promoter mutations in the nested variant of urothelial carcinoma: a clinicopathologic study with immunohistochemical and molecular correlates.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jun 2020
Taylor Alexander S, McKenney Jesse K, Osunkoya Adeboye O, Chan May P, Al-Ahmadie Hikmat A, Spratt Daniel E, Fullen Douglas R, Chinnaiyan Arul M, Brown Noah A, Mehra Rohit
Abstract excerpt
The nested variant of urothelial carcinoma, a frequent mimic of benign lesions on limited specimens, has been associated with high-stage disease including metastases at presentation. While PAX8 immunohistochemistry has been noted to be infrequently present in urothelial carcinoma in general, it has not been studied specifically in a cohort of nested urothelial carcinomas. Furthermore, TERT promoter mutation...
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