Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A gapmer aptamer nanobiosensor for real-time monitoring of transcription and translation in single cells.

Biomaterials - 1 Feb 2018

Wang Shue, Xiao Yuan, Zhang Donna D, Wong Pak Kin

Abstract excerpt

Transcription and translation are under tight spatiotemporal regulation among cells to coordinate multicellular organization. Methods that allow massively parallel detection of gene expression dynamics at the single cell level are required for elucidating the complex regulatory mechanisms. Here we present a multiplex nanobiosensor for real-time monitoring of protein and mRNA expression dynamics in live cells...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aptamers, Nucleotide
Share to Biosensing Techniques
Share to Computer Systems

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Human Umbilical Vein Endothelial Cells

Share to Imaging, Three-Dimensional

Share to Microvessels

Share to Nanoparticles

Share to Single-Cell Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 29190498
DOI: 10.1016/j.biomaterials.2017.11.026
PMCID: PMC5858577

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A gapmer aptamer nanobiosensor for real-time monitoring of transcription and translation in single cells.PMID 29190498Read ↗

A novel gapmer nanobiosensor for probing long noncoding RNAs (lncRNA) expression dynamics during osteogenic and adipogenic differentiationSemantic proximity Read ↗

Probing Notch1-Dll4 Signaling in Regulating Osteogenic Differentiation of Human Mesenchymal Stem Cells using Single Cell NanobiosensorSemantic proximity Read ↗

Probing Notch1-Dll4 Signaling in Regulating Osteogenic Differentiation of Human Mesenchymal Stem Cells using Single Cell NanobiosensorSemantic proximity Read ↗

Single Living Cell Analysis Nanoplatform for High-Throughput Interrogation of Gene Mutation and Cellular Behavior.Semantic proximity Read ↗

Rapid Identification of Cell Types and Phenotypic States Using a One-Polymer Multichannel Nanosensor Fabricated via Flash Nanoprecipitation.Semantic proximity Read ↗

Rapid Naked-Eye Tracking of On-Cell Phenotype Based on Dual-Aptamer-Weaved Cascade Assembly of Nanostructures.Semantic proximity Read ↗

Targeted RNA Condensation in Living Cells via Genetically Encodable Triplet Repeat TagsSemantic proximity Read ↗

Sensitive single‐molecule protein quantification and protein complex detection in a microarray formatSemantic proximity Read ↗

Establishing an RNA sensor with high sensitivity and dynamic range utilizing a signal amplifier platformSemantic proximity Read ↗

Modular DNA-origami-based nanoarrays enhanced cell binding-affinity through “lock-key” interactionSemantic proximity Read ↗

Nanobiosensors for Single-Molecule Diagnostics: Toward Integration with Superresolution ImagingSemantic proximity Read ↗

Threading Precision: Recent Advances and Emerging Trends in Aptamer-Based Nanopore SensingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.