Article
Single Living Cell Analysis Nanoplatform for High-Throughput Interrogation of Gene Mutation and Cellular Behavior.
Nano letters - 9 Jun 2021
Dong Zaizai, Yan Shi, Liu Bing, Hao Yongcun, Lin Long, Chang Tianrui, Sun Hong, Wang Yusen, Li Hu, Wu Han, Hang Xinxin, He Shiqi, Hu Jiaming, Xue Xinying, Wu Nan, Chang Lingqian
Abstract excerpt
The genetic heterogeneities in cancer cells pose challenges to achieving precise drug treatment in a widely applicable manner. Most single-cell gene analysis methods rely on cell lysis for gene extraction and identification, showing limited capacity to provide the correlation of genetic properties and real-time cellular behaviors. Here, we report a single living cell analysis nanoplatform that enables...
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