Article
Targeted diversity generation by intraterrestrial archaea and archaeal viruses.
Nature communications - 23 Mar 2015
Paul Blair G, Bagby Sarah C, Czornyj Elizabeth, Arambula Diego, Handa Sumit, Sczyrba Alexander, Ghosh Partho, Miller Jeff F, Valentine David L
Abstract excerpt
In the evolutionary arms race between microbes, their parasites, and their neighbours, the capacity for rapid protein diversification is a potent weapon. Diversity-generating retroelements (DGRs) use mutagenic reverse transcription and retrohoming to generate myriad variants of a target gene. Originally discovered in pathogens, these retroelements have been identified in bacteria and their viruses, but never in...
Topics
Join the communities discussing this publication.