Article
Of rings and spines: The multiple facets of Citron proteins in neural development.
Small GTPases - 1 Mar 2020
Bianchi Federico T, Gai Marta, Berto Gaia E, Di Cunto Ferdinando
Abstract excerpt
The Citron protein was originally identified for its capability to specifically bind the active form of RhoA small GTPase, leading to the simplistic hypothesis that it may work as a RhoA downstream effector in actin remodeling. More than two decades later, a much more complex picture has emerged. In particular, it has become clear that in animals, and especially in mammals, the functions of the Citron gene (CIT)...
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