Article
Th17 pathway in recent-onset autoimmune diabetes.
Cellular immunology - 1 Feb 2018
Fores Jéssica Pereira, Crisostomo Lindiane Gomes, Orii Noemia Mie, Santos Aritania Sousa, Fukui Rosa Tsuneshiro, Matioli Sergio R, de Moraes Vasconcelos Dewton, Silva Maria Elizabeth Rossi da
Abstract excerpt
AIMS: Evaluate the participation of IL-17 pathway in T1D pathogenesis. T helper 17 cells are potent, highly inflammatory cells that produce interleukin 17A (IL-17A), considered a mediator of various immune disorders. However, their role in Type 1 diabetes (T1D) pathogenesis in humans is not totally elucidated. METHODS: The expression of IL-17 Receptor A (IL-17RA) in peripheral T lymphocytes and IL-17A serum...
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