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Article

Exome Array Analysis of Nuclear Lens Opacity.

Ophthalmic epidemiology - 1 Jun 2018

Loomis Stephanie J, Klein Alison P, Lee Kristine E, Chen Fei, Bomotti Samantha, Truitt Barbara, Iyengar Sudha K, Klein Ronald, Klein Barbara E K, Duggal Priya

Abstract excerpt

PURPOSE: Nuclear cataract is the most common subtype of age-related cataract, the leading cause of blindness worldwide. It results from advanced nuclear sclerosis, or opacity in the center of the optic lens, and is affected by both genetic and environmental risk factors, including smoking. We sought to understand the genetic factors associated with nuclear sclerosis through interrogation of rare and low frequency...

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Identifiers

PMID: 29182452
DOI: 10.1080/09286586.2017.1406122
PMCID: PMC5851868

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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