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Article

Polygenic effects and cigarette smoking account for a portion of the familial aggregation of nuclear sclerosis.

American journal of epidemiology - 15 Apr 2005

Klein Alison P, Duggal Priya, Lee Kristine E, O'Neill Jennifer A, Klein Ronald, Bailey-Wilson Joan E, Klein Barbara E K

Abstract excerpt

Cataract is the most common cause of blindness worldwide. Nuclear cataract, an advanced stage of nuclear sclerosis, is the most common type of age-related cataract. The authors assessed data from 2,089 persons within 620 extended pedigrees who participated in the 1988-1990 Beaver Dam Eye Study in Wisconsin to determine whether the observed familial aggregation of nuclear sclerosis could be explained by...

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Identifiers

PMID: 15800262
DOI: 10.1093/aje/kwi102

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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