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Genetic and Environmental Factors in Age-Related Nuclear Cataracts in Monozygotic and Dizygotic Twins

15 Jun 2000

Abstract excerpt

BACKGROUND: Age-related cataracts are a major public health problem. The relative importance of genes and environment in the causation of nuclear cataracts, the most common form of age-related cataracts, is not known. METHODS: We studied 506 pairs of female twins (226 monozygotic and 280 dizygotic) who were 50 to 79 years old (mean, 62). The amount of nuclear cataract in the right and left eyes was determined...

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PMID: 10853001
DOI: 10.1056/nejm200006153422404

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