Article
Effect of LSR polymorphism on blood lipid levels and age-specific epistatic interaction with the APOE common polymorphism.
Clinical genetics - 1 Apr 2018
Xie T, Stathopoulou M G, Akbar S, Oster T, Siest G, Yen F T, Visvikis-Siest S
Abstract excerpt
The lipolysis stimulated lipoprotein receptor (LSR) is an apolipoprotein (Apo) B and ApoE receptor that participates in the removal of triglyceride-rich lipoproteins during the postprandial phase. LSR gene is located upstream of APOE, an important risk factor for cardiovascular disease (CVD). Since the APOE common polymorphism significantly affects the variability of lipid metabolism, this study aimed to...
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