Article
Lipolysis stimulated lipoprotein receptor: a novel molecular link between hyperlipidemia, weight gain, and atherosclerosis in mice.
The Journal of biological chemistry - 12 Sept 2008
Yen Frances T, Roitel Olivier, Bonnard Lionel, Notet Véronique, Pratte Dagmar, Stenger Christophe, Magueur Erwan, Bihain Bernard E
Abstract excerpt
The lipolysis-stimulated lipoprotein receptor, LSR, is a multimeric protein complex in the liver that undergoes conformational changes upon binding of free fatty acids, thereby revealing a binding site (s) that recognizes both apoB and apoE. Complete inactivation of the LSR gene is embryonic leth...
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