Article
Variation of the N-acetyltransferase 2 gene in a Romanian and a Kyrgyz population.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2006
Rabstein Sylvia, Unfried Klaus, Ranft Ulrich, Illig Thomas, Kolz Melanie, Rihs Hans-Peter, Mambetova Chinara, Vlad Mariana, Brüning Thomas, Pesch Beate
Abstract excerpt
As part of a project on environmental disasters in minority populations, this study aimed to evaluate differences in the sequence of N-acetyltransferase 2 (NAT2) as a metabolic susceptibility gene in yet unexplored ethnicities. Eight single nucleotide polymorphisms (SNP) in the NAT2 coding region and a variant in the 3' flanking region were analyzed in 290 unrelated Kyrgyz and 140 unrelated Romanians by...
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