Article
Association between effectiveness of tuberculosis treatment and cytochrome P-4502E1 polymorphism of the patients.
International journal of mycobacteriology - 1 Jan 2000
Antonenko Petro, Butov Dmytro, Kresyun Valentyn, Antonenko Kateryna, Butova Tetiana
Abstract excerpt
CONTEXT: The risk of antituberculosis (TB) drug-induced liver injury could be determined by patients' genotype polymorphism of the xenobiotic-metabolizing enzymes. To find the meaning of cytochrome P-4502E1 (CYP2E1) polymorphism in TB patients. Corresponding of CYP2E1 polymorphism in TB patients with the level of isoniazid and rifampicin as well as for the outcome and toxicity development during inpatient TB...
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