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Article

Drug-metabolising enzyme polymorphisms and predisposition to anti-tuberculosis drug-induced liver injury: a meta-analysis.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 1 Sept 2008

Sun F, Chen Y, Xiang Y, Zhan S

Abstract excerpt

BACKGROUND: Although some case-control studies have investigated the association between drug-metabolising enzyme (DME) gene polymorphisms and susceptibility to anti-tuberculosis drug-induced liver injury (ATLI), their results are conflicting, mainly due to limited power. OBJECTIVE: To review the literature systematically, by means of a meta-analytical review, to evaluate the putative association and provide a...

Read the complete abstract on PubMed

Topics

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Share to Antitubercular Agents
Share to Arylamine N-Acetyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chemical and Drug Induced Liver Injury

Share to Cytochrome P-450 CYP1A1

Share to Cytochrome P-450 CYP2E1

Share to Disease Susceptibility

Share to Glutathione Transferase

Share to Tuberculosis, Pulmonary

Source

Identifiers

PMID: 18713495

Genes

NAT2
GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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