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Article

The association between CYP2E1 polymorphisms and hepatotoxicity due to anti-tuberculosis drugs: a meta-analysis.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jun 2014

Sheng Yun-Jian, Wu Gang, He Hong-Yan, Chen Wen, Zou Yong-Sheng, Li Qin, Zhong Li, Huang Yong-Mao, Deng Cun-Liang

Abstract excerpt

BACKGROUND: Although there have been previous studies on the potential association between cytochrome P450 2E1 (CYP2E1) polymorphisms and the risk of anti-tuberculosis drug-induced hepatotoxicity (ATDH), the results have generally been controversial. METHODS: We searched Medline/PubMed, EMBASE, Web of Science, and the Cochrane Library using the following key words: cytochrome P450 2E1, CYP2E1, polymorphism,...

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Share to Antitubercular Agents
Share to Arylamine N-Acetyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2E1

Share to Hepatocytes

Share to Isoniazid

Share to Liver Failure, Acute

Share to Pyrazinamide

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Source

Identifiers

PMID: 24607341
DOI: 10.1016/j.meegid.2014.01.034

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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